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Apomorphine inhibits KCNH2. 3 / 3
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"Apomorphine and ropinirole blocked hERG channels and prolonged action potential duration over similar concentrations suggesting that these drug interact primarily with the hERG K + channel."
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"Stock solutions were prepared fresh daily and diluted into the bath solution containing a final concentration of 0.1% DMSO.The dopamine receptor agonists apomorphine, ropinirole, pergolide and sumanir[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Four dopamine receptor agonists, namely apomorphine, pergolide, ropinirole, and sumanirole (Table 1A) showed differential effects on human HERG currents, which were blocked by apomorphine, pergolide, and ropinirole, with IC -values of 2.4, 0.12, and 1.2 µM, respectively, and prolonged action potential duration, while sumanirole was widely ineffective [131]."
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