IndraLab

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"In this review, we will analyze new heterophilic interactions that CAMS in the nervous system are involved in, and discuss the elucidation of CAM mediated signal transduction pathways and how CAMS are[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"Consistent with this report, our functional enrichment analysis showed that increased CALM1 expression could activate the PI3K-Akt signaling pathway."

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"At the immediate site of the interaction, however, it can be anticipated that neuropeptide-CaM binding may modulate CaM- mediated signal transduction."

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"In some cases (e.g. CD44, N-cadherin) this CAM proteolysis additionally initiates an intracellular signalling pathway by the subsequent release of intracellular protein fragments, which participate in signal transduction.Many CAMs such as cadherins, selectins or members of the immunoglobulin superfamily are released as soluble forms in vitro and in vivo."