IndraLab

Statements

USP24 activates Neoplasms. 5 / 6
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"In addition, we also found that USP24 promoted cell proliferation and tumor growth of HCC in vitro and in vivo."
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"The USP24-specific inhibitor, USP24-i-101 alone or in combination with immunotherapy anti-CTLA4, profoundly reactivates T cell functions in the TME and markedly induces tumor inhibition."
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"The results indicated that USP24 knockdown significantly decreased tumor volume by 67% (P < 0.001) and reduced tumor weight by 43% (P < 0.001) relative to the shNC control group (Fig. 6H, I)."
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"Ubiquitin-specific peptidase 24 accelerates aerobic glycolysis and tumor progression in gastric carcinoma through stabilizing PLK1 to activate NOTCH1."
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"A recent publication found that USP24 accelerates aerobic glycolysis and tumor progression in gastric carcinoma through stabilizing PLK1 to activate NOTCH1 [28]."
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