IndraLab

Statements

CALM1 binds NTS. 4 / 4
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sparser
"In the absence or presence of scoparone (EC 50 , 5.54 μM), a pull-down assay was performed to compare the binding of CaM1 (K df , 0.61 μM) to peptides such as NT, CT1, CT1B, PreIQ, and IQ under 1 mM Ca 2+ ."
35572395
sparser
"Pull-down assays demonstrated that CaM1 was markedly bound to the NT, CT1, CT1B, PreIQ, and IQ peptides, whereas its binding to CT2, CT3, and CT1A was negligible ( xref a-d)."
35572395
sparser
"These findings indicated that CaM1 bound to both the NT and proximal CT motifs of L-VGCC."
35572395
sparser
"Although CaM1 binding to the NT region and PreIQ tended to be decreased, while binding to CT1 and CT1B tended to be only slightly increased, CaM1 binding to the IQ domain was markedly increased in the presence of scoparone (47.06%, xref a-b)."
35572395