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ATXN3 inhibits Phosphatase. 1 / 1

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"Recently, two research teams reported the interaction between ATX3 and PNKP, and discovered that polyQ expanded ATX3 inactivates PNKP phosphatase activity, causing persistent DNA damage and chronic activation of pro apoptotic signaling, which leads to SCA3 pathogenesis."

28180282

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ATXN3 inhibits Phosphatase. 1 / 1

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