IndraLab

Statements

USP13 activates ACLY. 3 / 6
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"USP13-KD also significantly decreased ACLY activity, while USP13 overexpression enhanced ACLY activity in the ACLY activity assay (XREF_SUPPLEMENTARY)."
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"USP13 upregulates ACLY and OGDH, two key regulators that drive glutaminolysis, ATP generation and lipid synthesis in cancer metabolism."
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"Next, we examined whether USP13 augments the stability of ACLY and OGDH."
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