IndraLab

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"These results confirm that the full-length IBV S protein could also interact with eIF3f."
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"The interaction between coronavirus S protein and eIF3f plays a functional role in controlling the expression of host genes, especially genes that are induced during coronavirus infection [35]."
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"Similar experiments were then performed to check if the full-length SARS-CoV S protein could also interact with eIF3f."
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"The interaction between coronavirus S protein and eIF3f plays a functional role in controlling the expression of host genes, especially genes that are induced during coronavirus infection [ xref ]."
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"However, immunofluorescent staining of cells expressing the two proteins clearly showed that the SARS-CoV S protein could interact with eIF3f and sequester the later to the site of S protein."
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"We show here that eIF3f could interact with the S protein from two coronaviruses, SARS-CoV and the coronavirus infectious bronchitis virus (IBV)."
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"The interaction between coronavirus S protein and eIF3f plays a functional role in controlling the expression of host genes, especially genes that are induced during coronavirus infection [XREF_BIBR]."
24740387
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"These results confirm that the full-length S protein can also interact with eIF3f."
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"Meanwhile, parallel experiments confirmed that eIF3f could also interact with the S protein of another coronavirus, the avian coronavirus infectious bronchitis virus (IBV)."
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"Co-immunoprecipitation experiments were then performed to check if the N-terminal region of IBV S protein equivalent to the SDC of SARS-CoV S protein could interact with eIF3f."
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"Co-immunoprecipitation experiments were then carried out to test if IBV S protein could interact with the endogenous eIF3f in IBV-infected cells."
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"The inhibitory effect on translation rendered by the interaction between coronavirus S protein and eIF3f may account for the observed differential induction of virus-inducible genes at the transcriptional and translational levels.Is the observed inhibition of translation by the interaction of coronavirus S protein with eIF3f beneficial to the virus?"
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"Analysis of HeLa cells expressing the Myc-tagged SDC either on its own or together with the Flag-tagged eIF3f by Western blot with anti-Myc monoclonal antibody led to efficient detection of the Myc-tagged SDC (Fig. 1a, Similar experiments were then performed to check if the fulllength SARS-CoV S protein could also interact with eIF3f."
18231581
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"Similar experiments were then performed to check if the full-length SARS-CoV S protein could also interact with eIF3f."
18231581
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"Co-immunoprecipitation was performed to check if IBV S protein could also interact with eIF3f."
18231581
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"Interaction of the Flag-tagged eIF3f with the N-terminal region of the IBV S protein (IBV SΔC)."
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"Furthermore, eIF3f can also interact with the S protein of SARS-CoV and infectious bronchitis virus (IBV) to inhibit expression of host genes ( xref )."
29173589
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"These results confirm that the full-length IBV S protein could also interact with eIF3f."
18231581
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"The authors suggested that the interaction between CoV S protein and eIF3f may play a functional role in controlling the expression of specific host genes, especially those that are induced by the viral infection."
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"The inhibitory effect on translation rendered by the interaction between coronavirus S protein and eIF3f may account for the observed differential induction of virus-inducible genes at the transcriptional and translational levels."
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"SARS-CoV S protein also interacts with the translation initiation factor eIF3f and inhibit host cell translation by preventing its nuclear import ( xref )."
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"These results confirm that the full-length S protein can also interact with eIF3f."
18231581
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"These results confirm that the full-length IBV S protein could also interact with eIF3f."
18231581
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"Interestingly, IBV-infected cells stably expressing a Flag-tagged eIF3f showed much higher translation of IL-6 and IL-8, suggesting that the interaction between coronavirus S protein and eIF3f plays a functional role in controlling the expression of host genes, especially genes that are induced during coronavirus infection cycles."
18231581
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"The authors suggested that the interaction between CoV S protein and eIF3f may play a functional role in controlling the expression of specific host genes, especially those that are induced by the viral infection."
27712623
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"Furthermore, eIF3f can also interact with the S protein of SARS-CoV and infectious bronchitis virus (IBV) to inhibit expression of host genes."
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"Interaction of eIF3f with the full-length SARS-CoV S protein."
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"The interaction between SARS-CoV S protein and eIF3f was further investigated by checking if the two proteins could form complexes in vitro."
18231581
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"These results confirm that the N-terminal portion of the SARS-CoV S protein can indeed interact with eIF3f.Confirmation of the interaction between SARS-CoV S protein and eIF3f by co-immunoprecipitation and immunofluorescence."
18231581
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"The inhibitory effect on translation rendered by the interaction between coronavirus S protein and eIF3f may account for the observed differential induction of virus inducible genes at the transcriptional and translational levels."
18231581
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"These results confirm that the full-length S protein can also interact with eIF3f."
18231581
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"We show here that eIF3f could interact with the S protein from two coronaviruses, SARS-CoV and the coronavirus infectious bronchitis virus (IBV)."
18231581
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"However, immunofluorescent staining of cells expressing the two proteins clearly showed that the SARS-CoV S protein could interact with eIF3f and sequester the later to the site of S protein."
18231581
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"Interestingly, IBV infected cells stably expressing a Flag tagged eIF3f showed much higher translation of IL-6 and IL-8, suggesting that the interaction between coronavirus S protein and eIF3f plays a functional role in controlling the expression of host genes, especially genes that are induced during coronavirus infection cycles."
18231581
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"The inhibitory effect on translation rendered by the interaction between coronavirus S protein and eIF3f may account for the observed differential induction of virus-inducible genes at the transcriptional and translational levels."
18231581
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"The interaction between coronavirus S protein and eIF3f plays a functional role in controlling the expression of host genes, especially genes that are induced during coronavirus infection [35]."
24740387
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"Co-immunoprecipitation was performed to check if IBV S protein could also interact with eIF3f."
18231581
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"Co-immunoprecipitation was performed to check if IBV S protein could also interact with eIF3f."
18231581
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"Co-immunoprecipitation experiments were then carried out to test if IBV S protein could interact with the endogenous eIF3f in IBV infected cells."
18231581
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"We next set up to study the functional consequence of the confirmed interaction between SARS-CoV S protein and eIF3f in vitro."
18231581
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"Is the observed inhibition of translation by the interaction of coronavirus S protein with eIF3f beneficial to the virus?"
18231581
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"Furthermore, eIF3f can also interact with the S protein of SARS-CoV and infectious bronchitis virus (IBV) to inhibit expression of host genes (Xiao et al., 2008)."
29173589
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"It is likely that eIF3f could gain access to the luminal side of the membranous compartments and interact with the S protein."
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"The authors suggested that the interaction between CoV S protein and eIF3f may play a functional role in controlling the expression of specific host genes, especially those that are induced by the viral infection.Using a yeast two-hybrid human protein library screen, Zhou et al. (2008) found that the SARS-CoV N protein binds to eukaryotic translation elongation factor 1 alpha (eEF1α), an integral part of the translational machinery; GTP-bound EF1alpha plays a key role in recruiting aminoacyl-tRNA to the A site of the 80S translation initiation complex during translation."
27712623
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"The interaction between SARS-CoV S protein and eIF3f was further investigated by checking if the two proteins could form complexes in vitro."
18231581
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"Is the observed inhibition of translation by the interaction of coronavirus S protein with eIF3f beneficial to the virus?"
18231581
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"We next set up to study the functional consequence of the confirmed interaction between SARS-CoV S protein and eIF3f in vitro."
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"These results substantiate the conclusion that SDC could interact with eIF3f and further demonstrate that the two proteins could form stable complexes in vitro.We next set up to study the functional consequence of the confirmed interaction between SARS-CoV S protein and eIF3f in vitro."
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"g002 Inhibition of protein synthesis by interaction of SARS-CoV S protein with eIF3f."
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"We next set up to study the functional consequence of the confirmed interaction between SARS-CoV S protein and eIF3f in vitro."
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"Interaction of SARS-CoV S protein with eIF3f."
18231581
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"Interestingly, IBV-infected cells stably expressing a Flag-tagged eIF3f showed much higher translation of IL-6 and IL-8, suggesting that the interaction between coronavirus S protein and eIF3f plays a functional role in controlling the expression of host genes, especially genes that are induced during coronavirus infection cycles."
18231581
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"We show here that eIF3f could interact with the S protein from two coronaviruses, SARS-CoV and the coronavirus infectious bronchitis virus (IBV)."
18231581
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"Similar experiments were then performed to check if the full-length SARS-CoV S protein could also interact with eIF3f."
18231581
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"Co-immunoprecipitation experiments were then carried out to test if IBV S protein could interact with the endogenous eIF3f in IBV-infected cells."
18231581
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"Interaction of IBV S protein with eIF3f and inhibition of the translation of a reporter gene."
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"g003 Interaction of the IBV S protein with eIF3f and inhibition of protein synthesis."
18231581
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"Meanwhile, parallel experiments confirmed that eIF3f could also interact with the S protein of another coronavirus, the avian coronavirus infectious bronchitis virus (IBV)."
18231581
sparser
"The interaction between SARS-CoV S protein and eIF3f was further investigated by checking if the two proteins could form complexes in vitro."
18231581
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"Interaction of the Flag-tagged eIF3f with the N-terminal region of the IBV S protein (IBV SDC)."
18231581
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"Confirmation of the interaction between the Flag-tagged eIF3f and the full-length IBV S protein by co-immunoprecipitation."
18231581
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"Co-immunoprecipitation analysis of the interaction between IBV S protein and the endogenous eIF3f in IBV-infected Vero cells."
18231581
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"These results substantiate the conclusion that SΔC could interact with eIF3f and further demonstrate that the two proteins could form stable complexes in vitro.We next set up to study the functional consequence of the confirmed interaction between SARS-CoV S protein and eIF3f in vitro."
18231581
sparser
"Co-immunoprecipitation experiments were then performed to check if the N-terminal region of IBV S protein equivalent to the SΔC of SARS-CoV S protein could interact with eIF3f."
18231581
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"Meanwhile, parallel experiments confirmed that eIF3f could also interact with the S protein of another coronavirus, the avian coronavirus infectious bronchitis virus (IBV)."
18231581
sparser
"SARS-CoV S protein also interacts with the translation initiation factor eIF3f and inhibit host cell translation by preventing its nuclear import (Xiao et al., 2008)."
33335518
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"Confirmation of the interaction between SARS-CoV S protein and eIF3f by co-immunoprecipitation and immunofluorescence."
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