IndraLab

Statements


USP7 deubiquitinates HIF1. 2 / 2
| 2

reach
"As expected, ectopically expressed USP7 decreased ubiquitination of endogenous HIF-1α, while depletion of USP7 promoted ubiquitination of endogenous HIF-1α (Fig. 5F-G)."

reach
"The accumulative USP7 resulted in deubiquitylation and stabilization of HIF-1α, thereby facilitating resistance to oxaliplatin."