IndraLab

Statements

IL10 increases the amount of TLR4. 9 / 14
1 | 5 3
isi
"We recruited 80 patients to measure the expression of HMGB1, IL-17, and IL-10; 55 patients were recruited to measure the expression of TLR2 and TLR4 in monocyte and CD1c+dendritic cells, and 30 volunteers were included as controls."
31858561
reach
"Binding sites for CREB have been identified in the IL-10 promoter, and mutation of the MSK phosphorylation site, Ser133, in CREB reduced TLR4 induced IL-10 transcription."
27795299
reach
"Toll like receptor (TLR) 2 and TLR4 mRNA, as well as TLR4 surface expression, were significantly up-regulated by IL-10 in adherent cells."
12525572
reach
"Neutrophils produced a significant increase of IL-8, IL-1beta and TNF-alpha after 3, 6 and 24 h of H. pylori challenge, respectively, whereas IL-10 increased after 24 h. Helicobacter pylori challenge increased TLR2 and TLR4 expression; and antibodies against TLR2 and TLR4 diminished significantly the H. pylori induced production of IL-8 and IL-10."
17892476
isi
"Preimplantation kidney biopsies from ECD (n=41) and SCD (n=39) were evaluated for real-time quantitative polymerase chain reaction (qPCR) gene expression using the TaqMan Gene Expression Array Plates system for genes TLR4, HMGB1, NFK-beta, MyD-88, INF-gamma, IL1-beta, TNF-alpha, CASP1, ICAM-1, IL-10, HO-1, HIF-1, MCP-1, TGF-beta, TRIF, TRAM, IRF-3, RIP1, INFbeta-1 and NLRP3."
31764760
reach
"Trauma-hemorrhage increased the production of IL-6, IL-10, IL-12 and TNF-alpha enhanced the expression of TLR4, MyD88 as well as the activation of MAPK proteins (p38, ERK and JNK) in epidermal keratinocytes."
17403539
isi
"Compared with the NC group, in the model group, the myocardial infarction was large; inflammatory cell infiltration was severe; apoptosis was enhanced; expression of TLR4, JAK2, and STAT3 was increased; and serum concentrations of IL-6, TNF-alpha, IL-10, and HMGB1 were significantly increased."
31847632
reach
"Of note, we have demonstrated that IL-10 administration suppressed the expression of FcgammaRI and enhanced the expression of TLR4 and CR3, which in turn prevented the survival of E. coli K1 in MO XREF_BIBR."
21124939
bel
"Toll-like receptor (TLR)2 and TLR4 mRNA, as well as TLR4 surface expression, were significantly up-regulated by IL-10 in adherent cells."
12525572