IndraLab

Statements



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"Similarly, the compound 293B, a blocker of basolateral KCNQ1 and KCNE3 K (+) channels effectively blocked Cl (-) secretion when applied to either the luminal or basolateral side of the epithelium."

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"The decrease in [Ca ] induced by chromanol 293B may explain the decrease in protein tyrosine phosphorylation levels during capacitation.Furthermore, our results indicate that KCNQ1 inhibition increased [Cl ] (Figure 4D)."