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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

Thioridazine inhibits KCNH5. 2 / 2

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"Thioridazine blocks EAG2 and reduces MB tumorigenicity."

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"It thus appears that thioridazine block of EAG2 potassium channel not only compromises its volume regulation crucial for human MB cell proliferation and motility, but also reduces the activity of KCNT2 potassium channel as a downstream effector of EAG2 channel activity (XREF_SUPPLEMENTARY)."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...