IndraLab

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USP15 binds COPS5. 3 / 3
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reach
"A distinct cross-talk between NF-kappaB pathway and CSN-signalosome was then confirmed by the fact that Jab1 and COPS5 controls NF-kB activity through CSN associated deubiquitinase USP15, which causes deubiquitination of IkappaBalpha, a negative feedback between degradation of IkappaBalpha and activation of NF-kappaB."
29535627
reach
"This is, for example, the case for CSN5, which, in addition to its own isopeptidase activity, is associated with USP15, both being required for proper processing of polyubiquitinated substrates bound to p97 and VCP XREF_BIBR - XREF_BIBR."
21124883
biogrid
No evidence text available
21145461