IndraLab

Statements

IL1A increases the amount of F3. 6 / 7
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"IL-1alpha enhanced the expression of IL-1alpha, IL-2, IL-6, and IL-8; nuclear factor of kappa light chain enhancer in B-cells (NFkappaB)-1, NFkappaB-2, and NFkappaB-inhibitor; cyclin dependent kinase inhibitor and monocyte chemotactic protein-1; and transiently increased tissue factor expression."
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"Up-regulation of TF expression by human TNFalpha or IL-1alpha shortened PEC induced coagulation time, while siRNA mediated knockdown of TF expression prolonged coagulation time."
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"For example, assembly of small amounts of terminal complement complexes on endothelial cells induces the production of IL-1alpha, which acts on endothelial cells in an autocrine manner to induce the e[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
11336689
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"Endotoxin, tumor necrosis factor (TNF-) and interleukin-1a (IL-1a) induce tissue factor expression, primarily on monocytes / macrophages [7, 8] and probably play a role in inducing tissue factor in atherosclerotic plaques as well [9]."
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"PCA and tissue factor level induced by IL-1alpha are lower in PDECs than in HSVECs."
17578711
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"Such a potentialization between glucocorticoids and IL-1 alpha was not observed for another marker of endothelial activation, IL-1 alpha induced stimulation of coagulation tissue factor expression."
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