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USP7 inhibits CCDC6. 2 / 2

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"A panel of HGSOC cell lines (either BRCA-wild type or mutant) were treated with PARPi after CCDC6 was attenuated by silencing or by inhibiting USP7, a CCDC6-deubiquitinating enzyme, and the effects on cell survival were assessed."

35964058

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"Meanwhile, CCDC6 was reported to be one of the substrates of USP7, which can prevent CCDC6 from ubiquitination and stabilize it."

33967786

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IndraLab

Statements

USP7 inhibits CCDC6. 2 / 2

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