IndraLab

Statements



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"In contrast, Z-YVAD-FMK, Ac-DEVD-CHO, and Ac-LEVD-CHO, which inhibit caspase-1, caspase-3/7, and caspase-4, respectively, did not restrict the cytotoxicity or pyroptotic morphological changes in 0909I E. piscicida infected ZF4 cells."

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"This enhancement was abolished when 0.5 mM of Ac-YVAD-CHO (inhibitor of casp-1) or Ac-DEVD-CHO (inhibitor of casp-3) was added to the reaction mixture [21]."

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"The aleurone layers treated with distilled water exerted caspase-1 and VPE activity, both of which were inhibited by the caspase-1 specific inhibitor Ac-YVAD-CMK but not by the caspase-3 specific inhibitor Ac-DEVD-CHO."

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"This effect was inhibited by the tetrapeptide Ac-DEVD-CHO, a competitive inhibitor of the interleukin-1 beta converting enzyme (ICE)-related protease CPP32, but was not influenced by Ac-YVAD-CHO and Ac-YVAD-CMK, two specific inhibitors of ICE."