IndraLab

Statements

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"Down-regulation of USP44 promotes the apoptosis of glioma cells in vitro."
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"USP44 knockdown partially abolished NOVA1-induced cell proliferation and inhibition of apoptosis ."
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"Experimental studies have found that the expression level of USP44 is significantly reduced in CRC and enhances the apoptosis of CRC cells, indicating that USP44 is a cancer suppressor of CRC."
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"Another DUB, USP44, promotes the apoptosis of CRC cells via Axin1 deubiquitination and the Wnt signaling pathway [128]."
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"Meanwhile, downregulating USP44 also induced apoptosis."
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"Downregulation of USP44 expression can inhibit proliferation, migration and invasion of established glioma cell lines and induce apoptosis (85)."
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"Zhang et al. showed that the expression level of USP44 was markedly decreased in colorectal cancer, and USP44 overexpression inhibited proliferation and enhanced apoptosis in colorectal cancer cells (Huang et al., 2020)."
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"USP44 suppressed the growth and metastasis, and induced apoptosis 10-14."
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"USP44 is significantly downregulated in CRC and enhances the apoptosis of CRC cells."
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"This is consistent with our speculation that USP44 could accelerate DNA synthesis.USP44 also regulated apoptosis of cancer cells in a cell-dependent way."
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