IndraLab

Statements

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"YOD1 inhibits migration and invasion of HNSCC cells in vitro."
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"However, opposite outcomes were observed in the two cell lines after transfection, as YOD1 deficiency obviously accelerated migration and invasion in SCC15 and SCC25 cells (Fig. 3C, D)."
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"All results indicate that YOD1 inhibits the migration and invasion of HNSCC cells."
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"Furthermore, YOD1 knockdown promoted cell migration and invasion, whereas YOD1 overexpression inhibited those processes (Fig. 2H)."
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"Conversely, increased YOD1 expression blocks ERK signaling by stabilizing TRIM33 activation, thereby inhibiting tumor invasion and lymph node metastasis in squamous cell carcinoma of the head and neck [25]."
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"The results of the in vitro and in vivo experiments verified that YOD1 depletion significantly promoted growth, invasion, and epithelial-mesenchymal transition in HNSCC."
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