IndraLab

Statements

Protease activates KCNH2. 2 / 2
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"To study the cell surface expression of hERG channel proteins, the intact cells transfected with WT hERG or the splice mutant were treated with proteinase K."
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"This evidence provides new insight into the relationship between hypoxia and ischemic heart disease, suggesting that damage to the hERG mediated by proteases may contribute to ischemia-associated QT prolongation and sudden cardiac death."
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