IndraLab

Statements

OTUB1 binds UBE2E1. 11 / 11
5 | 2 4
biogrid
No evidence text available
33961781
biogrid
No evidence text available
28073915
biogrid
No evidence text available
26752685
reach
"We verified that there was no interaction of Ubc9 with components of the ubiquitin pathway, such as the DUB (deubiquitinating enzyme) OTUB1 (XREF_FIG), and a UBE2E1 and OTUB1 interaction, used as a positive control, was detected, as expected."
32184235
reach
"Because UBE2E1 is known to bind OTUB1 (17), this raises the possibility that OTUB1 may stabilize UBE2E1 directly by forming an OTUB1–UBE2E1 complex."
30282802
sparser
"Because UBE2E1 is known to bind OTUB1 ( xref ), this raises the possibility that OTUB1 may stabilize UBE2E1 directly by forming an OTUB1–UBE2E1 complex."
30282802
sparser
"Furthermore, one study has also revealed that OTUB1 can associate with ubiquitin conjugating enzyme E2 E1 (UBE2E1) through its non-catalytic activity, suppressing its autoubiquitination and hence, its proteasomal degradation."
38455765
sparser
"We verified that there was no interaction of Ubc9 with components of the ubiquitin pathway, such as the DUB (deubiquitinating enzyme) OTUB1 ( xref ), and a UBE2E1 and OTUB1 interaction, used as a positive control, was detected, as expected."
32184235
biogrid
No evidence text available
35927303
biogrid
No evidence text available
32049508
sparser
"Because all members of the UBE2E family can autoubiquitinate themselves in vitro ( xref , xref ), the mechanism of stabilization we observed for OTUB1-UBE2E1 likely extends to UBE2E2 and UBE2E3."
30282802