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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP36 inhibits IMD. 2 / 2

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"Another recent study demonstrated that the deubiquitinating enzyme Usp36, which had been shown to negatively regulate the IMD pathway in flies, also negatively regulates p62 dependent selective autophagy in flies and human cells [XREF_BIBR]."

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"USP36 removes K63-polyubiquitin chains from IMD and then appears to increase the addition of K48-ubiquitin chains and degradation of IMD."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...