IndraLab

Statements

USP18 binds USP20 and STING1. 4 / 4
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"Our above results demonstrated that (1) USP18 and USP20 correlate with limited oHSV-1 T1012G virus yields in SCC9 cells; (2) USP18 and USP20 interact with STING and alter the levels of STING proteins in SCC9 cells; and (3) altered STING accumulation regulates viral replication in SCC9 and SCC25 cells, while we need to further examine whether the DUB activity of USP18 or USP20 is crucial for the regulation of STING stabilization and oHSV-1 T1012G virus replication."
34901390
sparser
"Collectively, these results showed that USP18 and USP20 interact with STING and that a deficiency of either USP18 or USP20 affects the stability of STING in SCC9 cells."
34901390
sparser
"Immunoprecipitation revealed that both USP18 and USP20 interacted with the N-terminal region of the STING protein."
33138315
sparser
"We found that USP18 and USP20 both interact with STING in SCC9 cells."
34901390