IndraLab
Statements
sparser
"The abl-1 /Abl kinase, which interacts with ABI-1, a cytoskeletal regulatory protein of the WASP-family verprolin-homologous (WAVE) protein complex, can suppress ced mutant phenotypes in the DTC. xref Mutations in the C. elegans homolog of the Drosophila Cactus binding protein Cactin/CACN-1 enhanced the ced-10 mutant phenotypes. xref Although the molecular mechanisms governing the interactions of CACN-1 or ABL-1 with CED-10 or MIG-2 have not been deciphered, the genetic data support potential roles for these molecules in modulating Rac signaling between adhesion and cytoskeletal dynamics."