IndraLab

Statements

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"The EEF1A1/UCHL3 axis promotes HCC cell malignant and drug resistance."
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"Functional experiments and nude mouse models have demonstrated that the UCHL3/EEF1A1 axis promotes the migration, stemness, and drug resistance of HCC cells."
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"However, the effects of the UCHL3/EEF1A1 axis on HCC tumors as revealed by patient-derived xenograft (PDX) models remains to be explored.Therefore, UCHL3 and EEF1A1 jointly promote the migration, stemness, and drug resistance of HCC cells, as well as influencing the growth of mouse tumor models."
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"UCHL3 enhances drug resistance and glycolysis in pancreatic cancer through the stabilization of FOXM1 and upregulation of LDHA [6, 7]."
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