IndraLab

Statements

reach
"Previous studies have shown that PRRSV nsp1α/β modulates type I IFN response by blocking dsRNA-induced IRF-3 activation and IFN promoter activities, but IRF-3 phosphorylation and its nuclear translocation occur normally in the presence of the nsp1α/β [51]."
24967365
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"By binding to dsRNA NS1 disguises the viral dsRNA pattern from the cytoplasmic receptors and inhibits IFN-α/INF-β induction via IRF3 (Garcia-Sastre, 2004; Talon et al., 2000)."
18086372
reach
"By binding to dsRNA NS1 disguises the viral dsRNA pattern from the cytoplasmic receptors and inhibits IFN-a/INF-b induction via IRF3 (Garcia-Sastre, 2004; Talon et al., 2000) ."
18086372
reach
"Previous studies have shown that PRRSV nsp1 / modulates type I IFN response by blocking dsRNA-induced IRF-3 activation and IFN promoter activities, but IRF-3 phosphorylation and its nuclear translocation occur normally in the presence of the nsp1 / [51] ."
24967365