IndraLab

Statements


SAR inhibits KCNH2. 2 / 2
| 2

reach
"41 Extensive SAR studies commenced to reduce the hERG channel affinity of the molecules while retaining all other desirable pharmacological properties."

reach
"SAR studies of this ion channel have shed light on the structural requirements for hERG interaction but most importantly may reveal drug design principles to reduce hERG affinity."