IndraLab

Statements

USP7 inhibits FOXO. 5 / 5
| 4 1
reach
"However, USP7 does negatively regulate FOXO transcriptional activity towards endogenous promoters."
16964248
reach
"While USP7 inhibits Foxo through deubiquitination it has no effect on protein levels of Foxo reinforcing the view that monoubiquitination of Foxo acts independent of protein degradation."
21443461
reach
"The SET9 and USP7 genes disrupt the FOXO (forkhead box O) signaling pathway."
37913711
reach
"While the ubiquitin ligase responsible for this effect has not yet been identified, de-ubiquitination is carried out by the de-ubiquitinating enzyme USP7/HAUSP thereby negatively regulating FOXO activ[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
22115564
sparser
"While USP7 inhibits Foxo through deubiquitination it has no effect on protein levels of Foxo reinforcing the view that monoubiquitination of Foxo acts independent of protein degradation."
21443461