IndraLab

Statements

COPS5 inhibits cell cycle. 5 / 6
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"Moreover, deletion of CSN5 caused cell cycle arrest rather than inducing apoptosis."
34247597
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"CSN5 and Jab1 elimination inhibited progression of the cell cycle at multiple points, seemed to initiate p53 independent senescence and increased the ploidy of cells."
20974137
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"The co-transfection of Jab1 with BRSK2 reduced cell cycle arrest at G2/M phase from 30% to 19%."
22609399
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"As the cellular abundance of p27 is an indicator of cell cycle, we thus reviewed relative articles to find whether the cell cycle arrest effect caused by COPS5 or COPS6 inhibition was p27 dependent."
28919423
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"We found that in Schwann cells, cell cycle arrest caused by loss of COPS5 could be restored by genetic depletion of p27 [18]."
28919423