IndraLab

Statements

USP18 binds IFNAR. 4 / 5
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reach
"In this case, STAT2 was able to bind USP18, but USP18 interaction with IFNAR was impaired, leading to prolonged type I IFN signaling (49)."
37126806
sparser
"In this case, STAT2 was able to bind USP18, but USP18 interaction with IFNAR was impaired, leading to prolonged type I IFN signaling ( xref )."
37126806
reach
"They further demonstrated that white matter microglia from mice with a different point mutation disrupting the interaction between USP18 and IFNAR showed prolonged STAT1 activation mirroring the interferon signaling findings in the USP18 KO mice [XREF_BIBR]."
28540600
sparser
"What are the host determinants for ISG15’s species-specific effect on the IFNAR–USP18 axis?"
37573184