IndraLab

Statements

USP6 deubiquitinates JAK1. 4 / 4
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"We previously showed that ubiquitin specific protease 6 (USP6) directly deubiquitinates and stabilizes Jak1, thereby inducing an IFN signature in ES cells."
33558334
reach
"To test whether USP6 can induce de-ubiquitination of Jak1 in vivo, HeLa cells were co-transfected with FLAG-Jak1, Myc-Ub, and HA-USP6 alleles."
27440725
reach
"We found that USP6 directly deubiquitinated Jak1, leading to its stabilization and activation of STAT3."
27440725
trips
"We found that USP6 directly deubiquitinated Jak1, leading to its stabilization and activation of STAT3."
27440725