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USP8 deubiquitinates LEPR. 2 / 2

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"Bland and colleagues suggested that leptin increases the expression of USP8, which in turn deubiquitylates the leptin receptor by cleaving Lys48-ubiquitin chains, among other (still unknown) chain types."

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"USP8 deubiquitinates the leptin receptor and is necessary for leptin mediated synapse formation."

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INDRA sources:

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Statements

USP8 deubiquitinates LEPR. 2 / 2

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