IndraLab

Statements


USP26 activates RAD51. 2 / 2
| 2

reach
"Loss of USP26 and USP37 function markedly impairs the assembly of PALB2, RAD51 and efficient HR."

reach
"Together, these results suggest that USP26 and USP37 promote the BRCA1 dependent loading of PALB2 and RAD51 by counteracting the repressive impact of RAP80 dependent BRCA1 sequestration and RAP80 dependent inhibition of end-resection during HR."