IndraLab

Statements


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"Here, we showed that CD166 and CD44 interaction is crucial for liver cancer cells with a negative feedback loop."

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"Taken together, these experiments revealed that there exists a negative feedback loop in the Bel-7402, and the interaction between CD166 and CD44 promote liver cell tumorigenesis ( Fig. 4 E)."

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"CD44 and ALCAM (CD166) have consistently been associated with tumor growth in xenografts."

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"In several KRAS mutated cancers, the CD44 molecule associates with ALCAM/CD166 promoting an aggressive phenotype that predicts worse outcome and increased risk of liver and lung metastasis (e.g., colon cancer) (29)."