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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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USP13 deubiquitinates STAT1. 4 / 4

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"Congruently, STAT1 ubiquitination is reduced in cells by USP13 overexpression and increased with USP13 knockdown regardless of IFNa treatment (115) ."

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"Congruently, STAT1 ubiquitination is reduced in cells by USP13 overexpression and increased with USP13 knockdown regardless of IFNα treatment (115)."

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"A recent report suggested that the deubiquitinase USP13 decreased STAT1 ubiquitination, which however was independent of IFNs treatment [XREF_BIBR]."

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"More specifically, USP13 positively regulates the antiviral activity of IFNa against DEN-2 virus replication by deubiquitinating and stabilizing STAT1 (115) ."

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USP13 deubiquitinates STAT1. 4 / 4

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