IndraLab

Statements

USP13 deubiquitinates STAT1. 4 / 4
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"Congruently, STAT1 ubiquitination is reduced in cells by USP13 overexpression and increased with USP13 knockdown regardless of IFNa treatment (115) ."
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"Congruently, STAT1 ubiquitination is reduced in cells by USP13 overexpression and increased with USP13 knockdown regardless of IFNα treatment (115)."
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"A recent report suggested that the deubiquitinase USP13 decreased STAT1 ubiquitination, which however was independent of IFNs treatment [XREF_BIBR]."
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"More specifically, USP13 positively regulates the antiviral activity of IFNa against DEN-2 virus replication by deubiquitinating and stabilizing STAT1 (115) ."
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