IndraLab

Statements


USP15 increases the amount of FOXC1. 4 / 4
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"That is to say, the Exos of USP15 overexpressed achieved the repair effect on LPS-induced chondrocyte damage by expediting the level of FOXC1."

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"Besides, USP15 was validated to exert a deubiquitination effect by binding to FOXC1 and positively regulate FOXC1 expression."

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"In brief, USP15 positively regulated FOXC1 expression through deubiquitination."

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"In summary, this indicated that ADMSC-Exo overexpressing USP15 induced macrophages polarization from M1 to M2 by facilitating the expression of FOXC1 protein."