IndraLab

Statements

USP30 inhibits mutated PRKN. 2 / 2

| 2

reach

"Early studies on USP30 focused on reversal of Parkin dependent MOM ubiquitylation in HeLa cells overexpressing Parkin, as well as in Drosophila, where reduction in USP30 function enhanced the activity of Parkin mutants."

32142685

➶

reach

"In addition, loss of USP30 can promote the activity of mutant Parkin alleles."

32142685

INDRA sources:

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IndraLab

Statements

USP30 inhibits mutated PRKN. 2 / 2

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