IndraLab

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"Studies have reported that USP4 could inhibit breast cancer cell growth by upregulating PDCD4 [ xref ]."

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"Previous studies have shown that USP4 expression was significantly decreased in breast cancer tissue and that USP4 inhibited breast cancer cell growth through inhibiting PDCD4 degradation. xref USP4 was downregulated in lung adenocarcinoma and served as an independent predictor. xref Some other studies claimed that USP4 might have oncogenic properties."

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"These results suggest that USP4 inhibits breast cancer cell growth and proliferation in vivo."