IndraLab

Statements

Ethanol inhibits CASP1. 9 / 11
| 1 8
reach
"And, similar to J774 cells, ethanol treatment prevented the cleavage and secretion of both IL-1beta and caspase-1 from human PBMCs (XREF_FIG)."
27421477
reach
"Ethanol Inhibits Activation of Caspase-1."
24244322
reach
"The additional application of EtOH to sodium orthovanadate at the first time point significantly decreased the caspase-1 activity, but less so than EtOH does in the LPS and ATP group."
32366053
reach
"Alcohol buildup has been reported to inhibit caspase-1 and increase the production of IL-18 and IL-1 in esophageal epithelial cells, both of which are associated with pyroptosis [57]."
36055576
reach
"In line of this hypothesis, here we found that ethanol induced activation of Caspase-1, as well as cleavage of IL-1beta were attenuated in livers of MyD88 LysM-KO mice, suggesting that Myeloid-MyD88 contributes to ethanol induced liver injury through induction of pyroptosis."
28165624
reach
"These findings suggest that ethanol inhibits the autoproteolysis of caspase-1 by inhibiting the activation of inflammasome."
24244322
reach
"In addition, alcohol reduced pro caspase 1 but promoted caspase 1 activation in mice with tumors."
29245988
eidos
"Ethanol Diminishes Caspase-1 Activity and ASC Speck Formation In order to investigate the influence of ethanol on caspase-1 activation , EtOH was applied to HepG2 cells at two different time points to determine its mechanistical approach ."
32366053
reach
"Ethanol prevents the cleavage of pro-IL-1beta and pro-caspase-1 into their mature forms."
27421477