IndraLab

Statements

CASP8 activates USP28. 2 / 2
| 2
reach
"Accordingly, recombinant caspase-8 produced a robust and concentration dependent cleavage of recombinant USP28 in vitro and in whole cell lysates (XREF_SUPPLEMENTARY and XREF_SUPPLEMENTARY)."
31982308
reach
"Elevated nuclear expression of caspase-8 was recently reported to promote cleavage and inactivation of the ubiquitin-specific peptidase 28 (USP28), resulting in de facto p53 protein loss and cell cycle progression in a p53-proficient melanoma tumor model [34]."
36428594