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ATXN3 inhibits TP53. 1 / 3

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"ATX-3 deletion destabilizes p53, resulting in deficiency of p53 activity and functions, whereas ectopic expression of ATX-3 induces selective transcription and expression of p53 target genes and promotes p53 dependent apoptosis in both mammalian cells and the central nervous system of zebrafish."

27851749

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IndraLab

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ATXN3 inhibits TP53. 1 / 3

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