IndraLab

Statements

PNLIP inhibits USP7. 5 / 5
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"In summary, our findings reveal that PTL inhibits USP7 activity, identifying a potential mechanism by which PTL suppresses Wnt and beta-catenin signaling."
32029476
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"Besides, we previously discovered that PTL is a novel inhibitor of USP7 [ 22 ]."
34030041
sparser
"These data gave us a hint that the inhibition of USP7 by PTL may improve the sensitivity of ATO."
36353537
reach
"Here, we report that sesquiterpene lactone parthenolide (PTL) inhibits USP7 activity, assessed with deubiquitinating enzyme activity assays, including fluorogenic Ub-AMC and Ub-Rho 110, Ub-VME/PA labeling and Di-Ub hydrolysis assays."
32029476
reach
"These data gave us a hint that the inhibition of USP7 by PTL may improve the sensitivity of ATO."
36353537