IndraLab

Statements

USP44 inhibits APC_C. 2 / 3
| 2
reach
"Interestingly, a groundbreaking study from Dr. Elledge 's group identified that the deubiquitinating enzyme USP44 (ubiquitin specific protease 44) prevents the premature activation of the APC through stabilization of the APC-inhibitory Mad2 and Cdc20 complex [XREF_BIBR]."
23151139
reach
"Thus, Usp44 and Usp37 can restrict the activity of the major K11 specific ligase, the APC/C, in addition to deubiquitinating substrates modified with K11 linked chains."
21978762