IndraLab

Statements


| 2

reach
"These results suggested that the UIMs in USP37 contribute to the full enzymatic activity, but not ubiquitin chain substrate specificity, of USP37 possibly by holding the ubiquitin chain substrate in the proximity of the catalytic core."

reach
"In the context of DNA double-strand breaks (DSBs), USP37 and USP26 play pivotal roles in removing RNF168-induced ubiquitin conjugates from the BRCA1-A complex, without USP37 impairing DSB repair (22)."