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USP12 decreases the amount of Chemokine. 1 / 1
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"Given that USP12 negatively regulated protumourigenic chemokine expression and exerted a tumour-suppressive effect in immune-competent mice but not in immune-deficient mice, it seems intuitive to speculate that USP12 downregulation in tumours may help establish a favourable microenvironment for tumour growth."