IndraLab

Statements

OTUD6B increases the amount of SNAI1. 2 / 2
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"As expected, overexpression of OTUD6B increased, while knockdown of OTUD6B decreased, the ubiquitination level and degradation of SNAIL in ESCC cells (Figure 4D–G and Figure S4C–F, Supporting Information)."
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"Moreover, low OTUD6B expression is significantly correlated with decreased β‐TrCP and increased SNAIL protein level in ESCC tissues and predicts a poor prognosis in ESCC patients."
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