IndraLab

Statements

USP20 deubiquitinates CTNNB1. 3 / 4
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"Moreover, knockdown of USP20 increases beta-catenin polyubiquitination, which enhances beta-catenin turnover and cell sensitivity to chemotherapy."
29867130
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"In addition, USP20 depletion promotes the polyubiquitination of β-catenin, which facilitates β-catenin turnover and increases cell sensitivity to chemotherapy [31]."
37311739
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"Importantly, the inhibition of β-catenin and Twist1 effectively suppresses the stemness induced by USP4.Previous studies have shown that USP8 and USP20 can deubiquitinate β-catenin, while DUB3 and USP51 target Twist1 [50–53]."
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