IndraLab

Statements

ATM activates UCHL3. 3 / 4
2 | 1
trips
"Mechanistically, in response to DNA damage, the deubiquitinase UCHL3 is phosphorylated and activated by ATM."
27941124
signor
"The deubiquitinase UCHL3 is phosphorylated and activated by ATM. UCHL3, in turn, deubiquitinates RAD51 and promotes the binding between RAD51 and BRCA2. |Mutation of S75 (S75A) abolished the pSQ/TQ signal, suggesting that S75 is a major ATM phosphorylation site following DNA damage"
27941124
signor
"Mechanistically, in response to DNA damage, the deubiquitinase UCHL3 is phosphorylated and activated by ATM."
27941124