IndraLab

Statements

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"In this study, we examined the effect of UCHL1 inhibition by LDN, a specific inhibitor, on the development of AF in a murine model of Ang II-induced AF."
31700166
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"Both inhibition of UCHL1 by LDN and knockdown UCHL1 by siRNA downregulated TGF-β1-mediated expression of pro-fibrotic proteins in CFs."
32606430
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"To assess whether UCHL1 mediates post-MI cardiac fibrosis in vivo, we used LDN to inhibit UCHL1."
32606430
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"The inhibition of UCHL1 by LDN (a specific inhibitor) significantly reduced the Ang II-induced increase in blood pressure, atrial fibrillation, fibrosis, inflammation, and oxidative stress."
31700166