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KCNH2 binds KCNQ1-T587M. 1 / 1

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"Consistent with this result, FRET experiments demonstrated that both KCNQ1-WT and -R259C interacted with hERG in the cytosol and on the plasma membrane; however, the interaction between KCNQ1-T587M and hERG was observed only in the cytosol, and hERG proteins were seldom transported to the cell membrane, suggesting that the KCNQ1 T587M mutation impaired the trafficking of hERG to the cell membrane."

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IndraLab

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KCNH2 binds KCNQ1-T587M. 1 / 1

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