IndraLab

Statements


IDB activates KCNH2. 2 / 2
| 2

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"Strikingly, either Prostratin or IDB treatment enhanced the current density of hERG K + channels in a dose dependent pattern when we co-expressed hERG WT and hERG A561V at a ratio of 2:1."

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"Western blotting experiments showed that both Prostratin and IDB promoted trafficking of hERG WT -hERG A561V channels in a dose dependent pattern, as reflected by the elevated 155kD hERG proteins, which distributed outside the ER."