IndraLab

Statements

reach
"Although dexamethasone inhibited STAT1 activation via toll-like receptor signaling in peritoneal macrophages by inducing suppressor of cytokine signaling 1 (SOCS1), dexamethasone supports STAT1-dependent gene expression in human peripheral blood monocytes by recruiting PU.1 transcription factor to IFN-γ-activated sites."
36779842
reach
"A. phagocytophilum infection-induced IFNγ signaling leads to phosphorylation of Stat1 in mice (Choi and Dumler, 2013), and dexamethasone suppression of STAT1 activity in A. phagocytophilum-infected horses reduces inflammatory signaling and disease severity (Davies et al., 2011)."
37228668
reach
"3.5 Dexamethasone Fails to Inhibit STAT1 Activation upon Challenge with IFN-gamma or PbNK65 Extract and IFN-gamma."
29033931
reach
"Dexamethasone, sotrastaurin, and dasatinib significantly downregulated genes of the IFNG pathway (IRF1), MHC class I molecules (HLA-E), proteasome-related genes (PSME1,2), as well as STAT1 (Figure 7A,E-F; supplemental Figure 22B-D), when compared to the control DMSO-K562-NK–cell condition."
39792962